加拿大红豆杉中紫杉烷类成分的研究进展及药源危机解决方法探讨(6)
YANG Chun， KONG Ling-yi， WANG Jun-song
(1.Jiangsu Union Technical Institute， Lianyungang 222006， China；
2.Department of Natural Medicinal Chemistry， China Pharmaceutical University， Nanjing 210009， China)
[Abstract] Taxus canadensis distributed mainly in North America， such as northern Minnesota， Newfoundland， south to Wisconsin and Pennsylvania. Its composition has been shown to be very different from other species， and in recent years， some new skeletons also have been found in Canada yew. Through analysis of the taxanes content on various Taxus plants containing taxanes， the results showed a higher content of taxol in T. canadensis. Based on the current research on T. canadensis (from the research results of the author in recent years， as well as from studies of scholars in the field)， the paper outlined the research progress in recent years on the chemical constituents of taxane of T. canadensis and the spectral characteristics of various types of compounds. Besides， this paper analyzed the present research about solutions for the taxol drug source crisis.
[Key words] Taxus canadensis； chemical composition； taxane； taxol； anti-tumor
doi：10.4268/cjcmm20141103
[责任编辑 孔晶晶], http://www.100md.com(杨春 孔令义 汪俊松)
(1.Jiangsu Union Technical Institute， Lianyungang 222006， China；
2.Department of Natural Medicinal Chemistry， China Pharmaceutical University， Nanjing 210009， China)
[Abstract] Taxus canadensis distributed mainly in North America， such as northern Minnesota， Newfoundland， south to Wisconsin and Pennsylvania. Its composition has been shown to be very different from other species， and in recent years， some new skeletons also have been found in Canada yew. Through analysis of the taxanes content on various Taxus plants containing taxanes， the results showed a higher content of taxol in T. canadensis. Based on the current research on T. canadensis (from the research results of the author in recent years， as well as from studies of scholars in the field)， the paper outlined the research progress in recent years on the chemical constituents of taxane of T. canadensis and the spectral characteristics of various types of compounds. Besides， this paper analyzed the present research about solutions for the taxol drug source crisis.
[Key words] Taxus canadensis； chemical composition； taxane； taxol； anti-tumor
doi：10.4268/cjcmm20141103
[责任编辑 孔晶晶], http://www.100md.com(杨春 孔令义 汪俊松)