大黄素抗胆囊癌作用的研究进展(3)
[8] Xin-xing Li，Ying Dong，Wei Wang，et al. Emodin as an effective agent in targeting cancer stem-like side population cells of gallbladder carcinoma[J]. Stem Cells Development， 2013，22(4)：554.
[9] 成军. 现代细胞凋亡分子生物学[M]. 北京：科学出版社，2012.
[10] 杨润霞. 肿瘤侵袭转移理论的研究进展[J]. 职业与健康，2006，22(21)：1871.
[11] 王心华，甄永苏. 大黄素抑制人高转移巨细胞肺癌PG细胞的肿瘤转移相关性质[J]. 癌症，2001，20(8)：789.
[12] 程延安，贾晓黎. 大黄治疗肝胆疾病[J]. 世界最新医学信息文摘，2003，4(2)：770.
[13] R D Irwin，J R Bucher，R E Chapin，et al. NTP technical report on the toxicology and carcinogenesis studies of emodin[J]. North Carolina： NIH Publication， 2001.
Research progress of emodin anti-gallbladder carcinoma
WANG Rui-tao， YIN Han， DONG Shun-bin， YUAN Wei， LIU Yan-ping， LIU Chang
(Department of Hepatobiliary Surgery， the First Affiliated Hospital， Medicine College of
Xi′an Jiaotong University， Xi′an 710061， China)
[Abstract] Emodin is an effective active ingredient extracted from Chinese herbal medicine， which has the function of antimicrobial， anti-inflammatory， antioxidant and scavenging oxygen free radicals， inhibiting platelet aggregation， improving microcirculation， protecting various organs and tissues as well as a wide range of anti-tumor effect. Primary biliary gallbladder is a common malignant tumor resection rate and lack of effective adjuvant treatment. It has been confirmed that emodin has broad spectrum antitumor effect，whereas， whether it has curative effect in the treatment of gallbladder carcinoma there is no reliable clinical trials confirmed that its resistance to gallbladder carcinoma function needs further experimental research.In this review， we report the research progress of emodin anti-gallbladder carcinoma.
[Key words] emodin； gallbladder carcinoma； antitumor； review
doi：10.4268/cjcmm20141105
[责任编辑 陈玲], http://www.100md.com(王瑞涛 尹涵 董顺斌 袁伟 柳言平 刘昌)
[9] 成军. 现代细胞凋亡分子生物学[M]. 北京：科学出版社，2012.
[10] 杨润霞. 肿瘤侵袭转移理论的研究进展[J]. 职业与健康，2006，22(21)：1871.
[11] 王心华，甄永苏. 大黄素抑制人高转移巨细胞肺癌PG细胞的肿瘤转移相关性质[J]. 癌症，2001，20(8)：789.
[12] 程延安，贾晓黎. 大黄治疗肝胆疾病[J]. 世界最新医学信息文摘，2003，4(2)：770.
[13] R D Irwin，J R Bucher，R E Chapin，et al. NTP technical report on the toxicology and carcinogenesis studies of emodin[J]. North Carolina： NIH Publication， 2001.
Research progress of emodin anti-gallbladder carcinoma
WANG Rui-tao， YIN Han， DONG Shun-bin， YUAN Wei， LIU Yan-ping， LIU Chang
(Department of Hepatobiliary Surgery， the First Affiliated Hospital， Medicine College of
Xi′an Jiaotong University， Xi′an 710061， China)
[Abstract] Emodin is an effective active ingredient extracted from Chinese herbal medicine， which has the function of antimicrobial， anti-inflammatory， antioxidant and scavenging oxygen free radicals， inhibiting platelet aggregation， improving microcirculation， protecting various organs and tissues as well as a wide range of anti-tumor effect. Primary biliary gallbladder is a common malignant tumor resection rate and lack of effective adjuvant treatment. It has been confirmed that emodin has broad spectrum antitumor effect，whereas， whether it has curative effect in the treatment of gallbladder carcinoma there is no reliable clinical trials confirmed that its resistance to gallbladder carcinoma function needs further experimental research.In this review， we report the research progress of emodin anti-gallbladder carcinoma.
[Key words] emodin； gallbladder carcinoma； antitumor； review
doi：10.4268/cjcmm20141105
[责任编辑 陈玲], http://www.100md.com(王瑞涛 尹涵 董顺斌 袁伟 柳言平 刘昌)