甘草生物活性研究的某些新进展(2)
1.13 其他作用
甘草制剂治疗银屑病、血小板减少性紫癜、抗心率失常、肺结核、高胆固醇血症、尿崩症、热淋尿痛以及疱疹性角膜炎、巩膜炎、急性虹睫膜状炎等眼科疾患都有一定疗效 。
2 结论
综上所述，甘草的生物活性作用是多方面的，其应用已向抗病毒、抗艾滋病毒、抗癌、防癌、增强免疫力等领域拓展。随着分子生物学技术的发展，有关甘草及其复方生物活性作用的研究不断深入对甘草的研究一步步走向成熟，但由于甘草化学成分和复方药味间的作用不明确，故应在继承传统中医药理论的基础上，运用现代科学技术手段进一步从微观上进行研究。因此，深入进行该类药物的研究具有重要的意义。
参 考 文 献
[1] Xu QX，Zhou M.Outlines of Pharmacological Action of Glycyrrhizae.Journal of Practical Traditional Chinese Medicine(实用中医药杂志)，2005，21(7):450-451.
, 百拇医药
[2] Amarowicz R，Pegg RB，Rahimi Moghaddam P，et al.Free-radical scavenging capacity and antioxidant activity of selected-plant species from the canadian prairies.Food Chemistry，2004，84:551-562.
[3] Lee SE，Hwang HJ，Ha JS，et al.Screening of medicinal plant extracts for antioxidant activity.Life Sciences，2003，73:167-179.
[4] Wang LR，Li J，Dong YJ，et al.Effect of Glycyrrhiza Polysacchride on Growth Performance and Immunity Function in Mice.Acta Agriculturae Boreali-Occidentalis Sinica(西北农业学报)，2007(1):226-228.
, 百拇医药
[5] Tian QL，Guan YP，Zhang B，et al.Research Advances on Pharmacological Activities of Components in Licorice.Natural Product Research and Development(天然产物研究与开发)，2006(2):164-168.
[6] Cheng J M，Lin HJ，Hsu Y H，et al.A quantitative bioassayfor HIV-1 gene expression based on UV activation:effect of glycyrrhizic acid.Antiviral Research，2004，62(1):27-36.
[7] Wang NQ.Observation of the Therapeutic Effect of Compound Glycyrrhizin Injection on Chronic Viral Hepatitis.Modern Medicine Journal of China(中国现代医药杂志)，2007(1):120-121.
, http://www.100md.com
[8] Liu XJ，Zhang ZR，Li JY.Therapeutic effect of combined therapy of diammonium glycyrrhizinate with salviate milttiorrhize in treating chronic hepatitis B.Clinical Medicine of China(中国综合临床)，2002(2):36.
[9] Xiong WS.Observation of the Therapeutic Effects of Compound Glycyrrhizin on Chronic Hepatitis C That of No Curative Effect with Interferon.China Pharmacy(中国药房)，2005(5):53-54.
[10] Romero M R，Thomas E，Serrano M A，et al.Effect of artemisinin/artesunate asinhibitorsof hepatitisB virus productionin an“invitro”replicative system.Antiviral Research，2005，68(2):75-83.
, 百拇医药
[11] Wang LN，Yu L，Zhang L，et al.Effects of glycyrrhizin on Proteinuria in rats with adriamycin nephropathy.Modern Journal of Integrated Traditional Chinese and Western Medicine(现代中西医结合杂志)，2007(4):34-38.
[12] Tamirs S，Eizenberg M，Somjen D，et al.Estrogen like activity of glabrene and other constituents isolated from licorice root.Journal of Steroid Biochemistry&Molecular Biology，2001，78:291-298.
[13] Kanazawa M，Satomi Y，Mizutani Y，et al.Isoliquiritigenin inhibits the growth of prostate cancer.European Urology，2003，43:580-586.
, 百拇医药
[14] Mauro S，Cristina F，Armanini D，et al.Glycyrrhetinic acid-induced permeability transition in rat liver mitochondria.Biochemical Pharmacology，2003，66(12):2375-2379.
[15] Liang B，huang FL，Hu BZ，et al.Research advances on chemical constituents and pharmacological activities in Glycyrrhiza.Journal of Northeast Agricultural University(实用中医药杂志)，2006(1):450-451.
[16] Liu YJ，Chen JH.Protective effects of Dammonii Glycyrrhizi natis against neuronal apoptosis induced by ischemia-reperfusion in rats.Chinese Pharmacological Bulletin(中国药理学通报)，2005，21(1):126-127.
[17] Yu H，Li CX，Gong LT，et al.Outlines of Pharmacological Action of Glycyrrhizae.Progress in Modern Biomedicine(现代生物医学进展)，2006(4):83-85., http://www.100md.com(邵玉蓝 曹 岗 熊耀康)
甘草制剂治疗银屑病、血小板减少性紫癜、抗心率失常、肺结核、高胆固醇血症、尿崩症、热淋尿痛以及疱疹性角膜炎、巩膜炎、急性虹睫膜状炎等眼科疾患都有一定疗效 。
2 结论
综上所述，甘草的生物活性作用是多方面的，其应用已向抗病毒、抗艾滋病毒、抗癌、防癌、增强免疫力等领域拓展。随着分子生物学技术的发展，有关甘草及其复方生物活性作用的研究不断深入对甘草的研究一步步走向成熟，但由于甘草化学成分和复方药味间的作用不明确，故应在继承传统中医药理论的基础上，运用现代科学技术手段进一步从微观上进行研究。因此，深入进行该类药物的研究具有重要的意义。
参 考 文 献
[1] Xu QX，Zhou M.Outlines of Pharmacological Action of Glycyrrhizae.Journal of Practical Traditional Chinese Medicine(实用中医药杂志)，2005，21(7):450-451.
, 百拇医药
[2] Amarowicz R，Pegg RB，Rahimi Moghaddam P，et al.Free-radical scavenging capacity and antioxidant activity of selected-plant species from the canadian prairies.Food Chemistry，2004，84:551-562.
[3] Lee SE，Hwang HJ，Ha JS，et al.Screening of medicinal plant extracts for antioxidant activity.Life Sciences，2003，73:167-179.
[4] Wang LR，Li J，Dong YJ，et al.Effect of Glycyrrhiza Polysacchride on Growth Performance and Immunity Function in Mice.Acta Agriculturae Boreali-Occidentalis Sinica(西北农业学报)，2007(1):226-228.
, 百拇医药
[5] Tian QL，Guan YP，Zhang B，et al.Research Advances on Pharmacological Activities of Components in Licorice.Natural Product Research and Development(天然产物研究与开发)，2006(2):164-168.
[6] Cheng J M，Lin HJ，Hsu Y H，et al.A quantitative bioassayfor HIV-1 gene expression based on UV activation:effect of glycyrrhizic acid.Antiviral Research，2004，62(1):27-36.
[7] Wang NQ.Observation of the Therapeutic Effect of Compound Glycyrrhizin Injection on Chronic Viral Hepatitis.Modern Medicine Journal of China(中国现代医药杂志)，2007(1):120-121.
, http://www.100md.com
[8] Liu XJ，Zhang ZR，Li JY.Therapeutic effect of combined therapy of diammonium glycyrrhizinate with salviate milttiorrhize in treating chronic hepatitis B.Clinical Medicine of China(中国综合临床)，2002(2):36.
[9] Xiong WS.Observation of the Therapeutic Effects of Compound Glycyrrhizin on Chronic Hepatitis C That of No Curative Effect with Interferon.China Pharmacy(中国药房)，2005(5):53-54.
[10] Romero M R，Thomas E，Serrano M A，et al.Effect of artemisinin/artesunate asinhibitorsof hepatitisB virus productionin an“invitro”replicative system.Antiviral Research，2005，68(2):75-83.
, 百拇医药
[11] Wang LN，Yu L，Zhang L，et al.Effects of glycyrrhizin on Proteinuria in rats with adriamycin nephropathy.Modern Journal of Integrated Traditional Chinese and Western Medicine(现代中西医结合杂志)，2007(4):34-38.
[12] Tamirs S，Eizenberg M，Somjen D，et al.Estrogen like activity of glabrene and other constituents isolated from licorice root.Journal of Steroid Biochemistry&Molecular Biology，2001，78:291-298.
[13] Kanazawa M，Satomi Y，Mizutani Y，et al.Isoliquiritigenin inhibits the growth of prostate cancer.European Urology，2003，43:580-586.
, 百拇医药
[14] Mauro S，Cristina F，Armanini D，et al.Glycyrrhetinic acid-induced permeability transition in rat liver mitochondria.Biochemical Pharmacology，2003，66(12):2375-2379.
[15] Liang B，huang FL，Hu BZ，et al.Research advances on chemical constituents and pharmacological activities in Glycyrrhiza.Journal of Northeast Agricultural University(实用中医药杂志)，2006(1):450-451.
[16] Liu YJ，Chen JH.Protective effects of Dammonii Glycyrrhizi natis against neuronal apoptosis induced by ischemia-reperfusion in rats.Chinese Pharmacological Bulletin(中国药理学通报)，2005，21(1):126-127.
[17] Yu H，Li CX，Gong LT，et al.Outlines of Pharmacological Action of Glycyrrhizae.Progress in Modern Biomedicine(现代生物医学进展)，2006(4):83-85., http://www.100md.com(邵玉蓝 曹 岗 熊耀康)