左卡尼汀治疗急性病毒性心肌炎疗效观察(1)
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[摘要] 目的 探讨左卡尼汀治疗急性病毒性心肌炎的临床效果。 方法 将急性病毒性心肌炎患者114例随机分为观察组与对照组，每组各57例，对照组给予常规治疗，观察组则在对照组的基础上加用左卡尼汀注射液治疗，比较两组的临床疗效。 结果 观察组总有效率为94.74%，明显优于对照组的77.19%，两组相比较，差异有统计学意义(P < 0.05)；治疗后两组的临床表现均比治疗前有明显的改善，而且观察组胸闷、胸痛、心悸的消失率明显高于对照组(P < 0.05)；观察组治疗后肌酸磷酸激酶(CPK)、天冬氨酸转氨酶(AST)、乳酸脱氧酶(LDH)较治疗前明显降低(P < 0.05)，观察组治疗后CPK和LDH明显低于对照组(P < 0.05)。 结论 左卡尼汀治疗急性病毒性心肌炎疗效确切，值得临床推广应用。
[关键词] 急性病毒性心肌炎；左卡尼汀；疗效；常规治疗
[中图分类号] R542.2+1 [文献标识码] A [文章编号] 1674-4721(2012)02(a)-0064-02
Curative effect observation of levocarnitine in treatment of acute viral myocarditis
LIANG Qingjia1 WANG Junrong2
1.Outpatient Department, Ailment Dispensary of Sanshui District in Foshan City of Guangdong Province, Foshan 528100, China; 2.Cardiology Department, the People's Hospital of Sanshui District in Foshan City of Guangdong Province, Foshan 528100, China
[Abstract] Objective To investigate the clinical effect of levocarnitine in the treatment of acute viral myocarditis. Methods One hundred and fourteen patients with acute viral myocarditis were randomly divided into the observation group and the control group, each group for 57 cases, patients in the control group were treated by conventional therapy, and on the basis of the control group, the observation group was treated by levocarnitine, and their clinical effects were compared. Results The total effective rate of the observation group was 94.74%, which was better than the control group's 75.51%, there were statistical significant difference. The clinical manifestation of the observation group was changed more, and the disappearance rate of the chest distress, chest pain, palpitation in the observation group were higher than those of the control group (P < 0.05). Conclusion The acute viral myocarditis is treated by levocarnitine and astragalus membranaceus injection has markedness effects, it is worth to popularize in the clinic.
[Key words] Acute viral myocarditis; Levocarnitine; Effect; Conventional therapy
病毒性心肌炎是心内科常见病，是指人体感染嗜心性病毒，引起心肌非特异性浸润，变性坏死或间质水肿为特征的心肌炎反应，引起该病最常见病毒是肠道病毒中的柯萨基B组病毒 ......
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