消银胶囊联合复方甘草酸苷治疗寻常型银屑病(1)
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[摘要] 目的 观察消银胶囊联合复方甘草酸苷治疗寻常型银屑病的临床疗效。 方法 将本院2009年1月～2011年6月收治的63例寻常型银屑病患者随机分为两组，对照组29例，口服消银胶囊5粒，3次/d，转移因子胶囊3 mg，2次/d，同时外用复方氟米松软膏。治疗组34例在此基础上加用复方甘草酸苷片50 mg，3次/d，两组均治疗6周观察疗效。 结果 治疗组治疗后PASI 评分为(3.61±2.26)分，低于对照组的(7.3±1.7)分，差异有统计学意义(P < 0.05)；两组患者治疗后的有效率分别为85.3%、65.5%，两组比较差异有统计学意义(P < 0.05)；两组患者治疗前后血、尿常规、肝肾功能等各项指标均未见异常。 结论 消银胶囊联合复方甘草酸苷治疗寻常型银屑病可明显提高疗效，值得临床应用。
[关键词] 消银胶囊；复方甘草酸苷；寻常型；银屑病
[中图分类号] R246.7 [文献标识码] A [文章编号] 1674-4721(2012)02(a)-0105-02
Xiaoyin granules in combination with compound Glycyrrhizin in the treatment of psoriasis vulgaris
ZHANG Wenxia1 SUN Chunting2
1. Department of Dermatology, Hospital of Zhengzhou University, Henan Province, Zhengzhou 450052, China; 2. Elementary and Primary School Health Care Stations of Zhengzhou City in Henan Province, Zhengzhou 450007, China
[Abstract] Objective To observe therapeutic effect of using Xiaoyin granules combining compound Glycyrrhizin in the treatment of psoriasis vulgaris. Methods Sixty three cases of psoriasis vulgaris patients in our hospital from January 2009 to June 2011 were divided into two groups randomly, in control group, 29 patients were given Xiaoyin granules 5 capsules, three times a day, and transfer factor capsules 3 mg, two times a day, taking orally, externally using orsalin ointment as well. In treatment group, 34 patients took compound Glycyrrhizin 50 mg orally, three times a day besides the above medical therapy, these two groups were observed the therapeutic effect for six weeks. Results After treatment, the PASI of treatment group was 3.61±2.26, it was lower than the control group with (7.3±1.7) score, there was significant difference between the two groups (P < 0.05); The effective rates in treatment group and control group were 85.3% and 65.5% respectively, there was significant difference between the two groups (P <0.05); The indices such as routine blood test, routine urine test, liver function, renal function etc. were all with no abnormality seen before and after treatment ......
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